First of all, as the directory structure of your installation is not readily apparent to me, I won't attempt to tell you *exactly* what values you should be using for some of your configuration setting variables - you should carefully review your DefaultSettings.php *and* your LocalSettings.php files for correct paths and urls for *your* installation.
Remember that you should only change setting in LocalSettings.php, never in DefaultSettings.php; in essence, you "overwrite", or supersede the values in DefaultSettings.php with an appropriate line in LocalSettings.php
There is excellent documentation on the use of LocalSettings.php, and the proper way to set the variables used in the file, in the MediWiki Manual section on Configuration Settings, and you should review that to make sure you have put the right "type" of value in each setting. 
From the LocalSettings.php file you referred me to in your last post, I can see that part of your problem is that you have placed a URL in a place where a *path* is called for:
You have:
In reply to:
$wgUploadPath = 'http://www.sixth-fleet.com/lcars-main/zeta-images/';
$wgUploadDirectory = 'http://www.sixth-fleet.com/lcars-main/zeta-images/';
$wgUploadPath appears to be correct (the URL of the upload directory). However, he reference I linked above clearly indicates that $wgUploadDirectory should be the "file system path" of the upload directory (and you have it entered as a URL, just as in the $wgUploadPath.
This is most likely what is producing your error message, as the program is trying to write to a "directory" that is not expressed in the manner expected (as a file system path). It's especislly confusing, as the error message includes the "string" from the variable, and such a "location" *does* exist, and *is* writable (if that directory is set to 755). I think that makes the error message particularly misleading.
For what it's worth, I also think it is very confusing, and non-intuitive, to require "file system paths" for variables named $wgxxxxDirectory *while* requiring URLS for variables named #wgxxxxPath , but that *is* MediaWiki's convention (go figure!
).
At any rate, that ought to get you on the right path to getting it sorted. I did not review other variables for a similar problem; I only looked at those relevant to the error message you reported. I suggest you carefully review them all, as I said at the beginning of this post. Good Luck!
--rlparker